|
• Involvement
of P38 MAPK and NO-mediator-intrinsic pathway signaling in male germ
cell apoptosis across species after hormone deprivation (3,1,2,4)
• Impairment of
spermatogenesis in transgenic mice with selective over expression of
Bcl-2 in the somatic cells of the testis. (3,1,2)
• gld and
lpr cg mice which harbor loss-of-functions in Fas-ligand
and Fas, respectively, confer no resistance to heat or hormone
deprivation induced programmed
germ cell death. (3,1,2)
• Involvement of
iNOS and programmed germ cell and neuronal death in male reproductive
aging. (4,3,2,1)
• XXY male mouse:
an experimental model for Klinefelter Syndrome. Molecular basis of
reproductive and conjunctive defects. (4,1,2,3)
• Progestogens
receptor in testis: a novel target for male contraception. (4,2,1)
• VASA
as a unique target to interfere with germ cell meiosis. (4,1,2,3)
• Mild
testicular hyperthermia but not hormone deprivation result in stag- and
cell-specific activation of ERK and Bcl-2 phosphorylation. (3,1,2,4)
•
Differential regulation of hormone and/or temperature on testicular gene
expression. (4,2,1,3) •
Mechanisms of testicular dysfunction induced by an extra X chromosome in
XXY mice. (4,1,2).
• Cellular and Molecular Mechanisms of
Impaired Neurobehavioral Phenotypes in XXY mice-Implication in men with
Klinefelter syndrome. (4,5,1,2).
• Stem cell transdifferentiation in the testis. (4,1,2). |
1. Ronald S. Swerdloff, M.D.
2. Christina Wang,
M.D.
3.
Amiya Sinha Hikim, Ph.D.
4. Yan-He Lue, M.D.
5. David Jentsch,
Ph.D.
|
|
